Andrew K. Sobering, PhD

Andrew K. Sobering, PhD
Associate Professor, Department of Biochemistry
Email: asobering@sgu.edu
Website: http://www.sgu.edu
Phone: (473) 439-2000 ext. 2069
Fax: (473) 444-1562



Biography

Click here to view complete Curriculum Vitae

Dr. Andrew K. Sobering received a BS, Biochemistry, magna cum laude from SUNY at Stony Brook, in Stony Brook, NY in 1994, and earned a PhD at Johns Hopkins University Bloomberg School of Public Health in Baltimore, MD in 2001. He continued at Johns Hopkins University with post doctoral research on the negative regulation of Ras signaling in yeast. He furthered his research career through the completion of a fellowship at the Faculté de Médecine-Necker, Paris, France with a project titled “role of S6 kinase in regulation of cell size”. During this time he was awarded the Poste Verte fellowship scholarship for outstanding research.

Dr. Sobering accepted a teaching position at the Medical University of the Americas (MUA), Nevis, West Indies, in 2005 and joined St. George’s University, School of Medicine, Grenada, as Associate Professor of Biochemistry in 2009.

Dr. Sobering is responsible for the submission of two patent applications through Johns Hopkins University, titled “Agents Capable of Inhibiting Ras and Uses Therof” (2002) and “Inhibition of GPI anchor production by Ras” (2004).

Areas of Interest
Investigations of natural toxins found in native Caribbean flora.
Selected Publications

Aguilar, V., Alliouachene, S., Sotiropoulos, A., Sobering, A., Athea, Y., Djouadig, F., Miraux, S., Thiaudiere, E., Froetz, M., Viollet, B., Diolez, P., Bastin, J., Benit, P., Rustin, P., Carling, D., Sandri, M., Ventura-Clapier, R., and Pende, M. 2007. S6 Kinase Deletion Suppresses Muscle Growth Adaptations to Nutrient Availability by Activating AMP Kinase. Cell Metabolism. 5, 476-487.

Sebastion K., Bonnet, C., Sobering, A. K., Ganesan, LP, and Silar, P. 2006. A mitotically inheritable unit containing a MAP kinase module. Proceedings of the American Academy of Sciences. 103, 13445-13450.

Ohanna M, Sobering AK, Lapointe T, Lorenzo L, Praud C, Petroulakis E, Sonenberg N, Kelly PA, Sotiropoulos A, Pende M. 2005. Atrophy of S6K1(-/-) skeletal muscle cells reveals distinct mTOR effectors for cell cycle and size control. Nature Cell Biology. 2005 Mar;7(3):286-94.

Sobering, A. K, Reika Watanabe, Martin J. Romeo, Benjamin C. Yan, Charles A. Specht, Peter Orlean, Howard Riezman, and David E. Levin. 2004. Yeast Ras regulates the complex that catalyzes the first step in GPI-anchor biosynthesis at the ER. Cell. 117:637-648.

Sobering, A. K., Romeo, M. J. Vay, H. A., and D. E. Levin. 2003. A Novel Ras Inhibitor, Eri1, Engages Yeast Ras at the Endoplasmic Reticulum. Mol. Cell Biol. 23:4893-4990.