Student should be able to recapitulate the important basic science concepts using clinical vignettes. It is a two-credit course with two lecture hour sessions usually on Fridays. The lecture hour sessions will be in the format of modified term-based learning. Students will be seated in groups of 12 to 14. Each group will be provided with a different clinical vignette related to the topics taught in the pathophysiology course that week. A number of basic science-related questions will be linked to the vignettes. The student groups get 10 to 12 minutes to discuss and find answers to the questions. At the end of that time, the plenary session will start. One by one, each vignette and the related questions are projected. The concerned group will respond with the answers. The rest of the class can then join in with any other relevant comments/disagreements. These sessions will be supplemented by online tasks in the form of MCQs or a similar format that the students will do under supervision. This course should enable the students to actively learn the application of Basic Sciences in the analysis and problem solving of clinical vignettes.